ADVANCES IN DRUGS OF EAR, NOSE AND THROAT IN RELATION TO PRESCRIPTIONS AND UTILIZATION PATTERN

Abstract

ABSTRACT

Objectives: This study reviewed the recent advances in drugs of ear, nose and throat (ENT) over two decades by identifying the priority conditions in children and adult, as well as the essential medicines used for treating these conditions, and identifying the impact of drug-nutrient interaction on metabolism of drugs and nutrition status of its users.

Method: A systematic electronic literature search of Medline/PubMed, ResearchGate, Cochrane reviews, and Web of Science was conducted for journals and published articles describing pattern of drug prescription in ENT medical Practice. Articles on pattern of ENT drugs prescribed, the impact of drugs on homeostasis of the body, and current trend of drug utilization were considered for review.

Results: A total of 43 articles were identified for this review. Most of the studies revealed prescribing more than one medication. Most commonly used antibiotic was Amoxicillin-Clavulanate followed by fluoroquinolones. Along with the antibiotics, analgesics and antihistamines were commonly prescribed. Mostly, antibiotics were prescribed without culture and sensitivity reports.

Conclusion: The reviews showed that more than one drug was prescribed, most of which were fixed dose combinations or by Brand name. Mainly, antibiotic was prescribed before culture and sensitivity tests, which may be the core factor of growing antibiotic resistance. Creating awareness among physicians via Continuous Medical Educations may overcome drug prescription pattern, drug-nutrient interactions, and drug utilization trend.